Anxiety is a naturally-occurring emotion and an innate response of the body to the environmental stimuli. Mild to moderate anxiety would increase level of performance.

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Anti-anxiety medications help reduce the symptoms of anxiety, such as panic attacks or extreme fear and worry. The most common anti-anxiety medications are called benzodiazepines. Benzodiazepines are a group of medications that can help reduce anxiety and make it easier to sleep.

Anxiety is a naturally-occurring emotion and an innate response of the body to the environmental stimuli. Mild to moderate anxiety would increase level of performance. However, when anxiety levels exceed the tolerability of a person, anxiety disorders may occur. People with anxiety disorders can exhibit fear responses such as defensive behaviors, high levels of alertness and negative emotions, without external stimuli which induce anxiety within an individual. Those with anxiety disorders are also often found to have concurrent psychological disorders, most commonly depression. Anxiety disorders are divided into 6 types in clinical recognition.

Medications

Anti-anxiety medication is any drug that can be taken or prescribed for the treatment of Anxiety disorders. Anxiety disorders can be mediated by neurotransmitters like norepinephrine, serotonin, dopamine, and gamma-aminobutyric acid (GABA) in the central nervous system. Anti-anxiety medication can be classified into six types according to their different mechanisms: antidepressants, benzodiazepines; buspirone; antiepileptics; antipsychotics; and beta-adrenoceptor antagonists.

Antidepressants including selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCA), Monoamine oxidase inhibitor (MAOI). SSRIs are used in all types of anxiety disorders while SNRIs are used for generalized anxiety disorder (GAD). Both of them are considered as first-line anti-anxiety medications. TCAs are second-line treatment as they cause more significant adverse effects when compared to the first-line treatment. Benzodiazepines are effective in emergent and short-term treatment of anxiety disorders due to their fast onset but carry the risk dependence. Buspirone is indicated for GAD, which has much slower onset but with the advantage of less sedating and withdrawal effects.

Anti-anxiety medications have been known to cause many adverse reactions as well as addiction and withdrawal symptoms.

How do anti-anxiety drugs and benzodiazepines work (mechanism of action)? Antidepressants reduce anxiety by increasing the concentration of chemicals (neurotransmitters) that the brain uses to communicate. These neurotransmitters include serotonin, norepinephrine, and dopamine.

Dosing

Anxiolytics are a type of medication primarily used to treat anxiety.

Dosage

⦁ Xanax, tablet ER, tablet ODT: 0.25-1 milligrams (mg), maximum of 4 mg per day.
⦁ Klonopin, tablet ODT: 0.5-1 mg, maximum of 20 mg per day.
⦁ Valium, tablet: 5-25 mg, maximum of 40 mg per day.
⦁ Ativan, tablet: 0.5-1 mg, up to 4 times per day5.

Side Effects of Anxiolytics?

Some short-term side effects of anxiolytics can include:

⦁ Slurred speech
⦁ Low heart rate
⦁ Low blood pressure
⦁ Irregular breathing
⦁ Memory loss
⦁ Confusion
⦁ Depression
⦁ Dizziness
⦁ Faulty judgment
⦁ Nausea
⦁ Nightmares

Long-term anxiolytic use can also cause side effects like:

⦁ Mood swings
⦁ Aggressive behaviour
⦁ Vision problems
⦁ Sleep problems
⦁ Breathing problems
⦁ Liver damage
⦁ Sexual problems
⦁ Chronic fatigue

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Anti-anxiety medications have been known to cause many adverse reactions as well as addiction and withdrawal symptoms.
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